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NAD+ 500mg research compoundEternaGen / Research use only

Research compound · Research use only

NAD+

From CA$90CAD

A coenzyme every cell uses to transfer energy and support core metabolic reactions.

Available to approved purchasers

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1
Documentation review pending Fulfilled in Canada Research use only

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NAD+From CA$90

Product information

NAD+, clearly explained.

A coenzyme every cell uses to transfer energy and support core metabolic reactions.

Overview

NAD+ is essential to normal cell biology, but that does not automatically prove that delivering more NAD+ creates broad wellness or anti-aging effects. Direct-infusion research is still limited and much smaller than the surrounding marketing suggests.

Nicotinamide adenine dinucleotide (NAD+) is an essential cellular coenzyme involved in redox reactions and a substrate for enzymes linked to DNA repair and signalling. Established cellular importance does not automatically validate a wellness intervention.
Format
Vial
Available strengths
500mg · 1000mg
Documentation
Source review pending
Research at a glanceCore biochemistry is established; direct-infusion clinical evidence remains limited
Reviewed 23 July 2026View research context

Specifications

Product details

Molecular formula
C21H27N7O14P2
Molecular weight
663.43 g/mol
Storage and handling
Protect from light and moisture. Follow the batch-specific handling record.
Batch documentationSource review pending

Supplier-origin documentation will be published only after EternaGen verifies the source and record details.

Not yet published
Important research-use boundary

Health Canada lists the named compound or components among unauthorized injectable drugs identified in the Canadian market. A research-use label does not make an unauthorized product suitable or legal for personal use.

Explore the research

What has been studied?

Keep the context attached

Check what was studied, what researchers observed, and the limitation attached to each finding.

Question 01

Cellular redox and energy metabolism

NAD+/NADH couples are central to metabolic reactions across cells and tissues.

Evidence so far: Established biochemistry
Question 02

Direct intravenous NAD+

A small pilot traced plasma and urinary metabolites during a six-hour infusion but did not test clinical efficacy.

Evidence so far: Very limited human pharmacokinetics
Question 03

NAD+ as an aging biomarker

A 2026 multi-cohort analysis found whole-blood NAD+ was stable with age and across lifestyle interventions, challenging a common assumption.

Evidence so far: Human biomarker evidence

Proposed mechanism

How researchers are investigating the mechanism.

NAD+ cycles between oxidized and reduced forms during energy metabolism. Cells also consume NAD+ through enzymes such as sirtuins, PARPs and CD38. Route and precursor choice materially affect absorption and metabolism.

Evidence gaps

What remains unknown?

  • Clinical efficacy of direct NAD+ infusion for anti-aging, energy, cognition or recovery is not established by the pilot evidence.
  • Blood NAD+ is not a validated universal measure of biological aging or tissue NAD+ status.
  • Precursor studies cannot be treated as direct evidence for externally administered NAD+.

Primary sources

Check the original sources.

  1. Direct-infusion pilotGrant et al. Human plasma and urine NAD+ metabolome during a six-hour infusion. Front Aging Neurosci. 2019. PMID 31572171.
  2. Human biomarker studyTrętowicz et al. Whole-blood NAD+ across age and lifestyle interventions. Nat Metab. 2026. PMID 42135539.
  3. Tolerability evidenceReyna et al. Retrospective NAD+ versus NR infusion pilot. Front Aging. 2026. PMID 41704678.

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